15 Best Injectable Peptides for Anti Aging (Top Guide)

Women pulling her cheek for best injectable peptides for anti aging article

There is a lot of information on the best injectable peptides for anti-aging.

There are also many different types of peptides available, so it can be challenging to determine which one is the best.

In this article, I will help you navigate through the maze of information and find the right peptide for your research.

What Are Peptides and What Do They Do?

Peptides are tiny molecules that play important roles in the body. They are made up of amino acids, which are the building blocks of proteins.

Peptides help to regulate many bodily functions, including digestion, energy production, and cell communication.

Some types also help to fight infection and musculoskeletal inflammation. Peptides are found in all body tissues, including the skin, muscles, and brain.

They can be used to treat a variety of health conditions. Sometimes they are taken as supplements to help improve energy levels, build muscle, and lose weight.

Studies are also being done on peptides as potential treatments for Alzheimer’s disease, cancer, and other diseases.

The Benefits of Peptide Injections

Peptide therapy is believed to have many benefits, including:

  • Improved lean muscle growth and muscle tone
  • Reduced inflammation
  • Enhanced athletic performance
  • Improved joint health
  • Increased collagen production
  • Stronger immune cells and immune response
  • Better skin tone and health
  • Reduced-fat storage
  • Stronger hair and nails
  • Many Peptides work to compensate for natural HGH decreases
  • Increased energy
  • Increased bone mass

The Best Injectable Peptides for Anti Aging

Below are some of the best injectable peptides for anti-aging.

Many of these also improve the body’s ability to promote immune system function, lean muscle mass, and weight loss.

1. Sermorelin

Sermorelin is a synthetic form of growth hormone-releasing hormones (GHRH), which occur naturally in the human body.

Sermorelin Acetate is a drug that is used to treat adult human growth hormone deficiency. It is also used off-label for anti-aging purposes, as well as for other conditions.

Benefits of Sermorelin

The main benefit of Sermorelin is that it can boost HGH production without crashing your natural levels.

This, in turn, can lead to several other benefits, such as reduced body fat, and increased muscle, and bone mass.

It may also help improve mood and increase energy levels.

Additionally, Sermorelin has been shown to boost the immune system, and it has also been used to treat conditions like Alzheimer’s disease and heart failure.

It is also approved by the FDA.

How Does Sermorelin Work?

Sermorelin is a peptide hormone that is used to stimulate the secretion of growth hormone from the pituitary gland.

Sermorelin is administered as an injection under the skin.

2. Thymosin Alpha-1

Thymosin alpha-1 is a peptide that helps to regulate the immune system.

It is often used to help treat cancer and HIV/AIDS, as well as other diseases that can affect the immune system.

This peptide is not FDA approved in the U.S.

Benefits of Thymosin Alpha-1

Some potential benefits of thymosin alpha-1 include:

  • Boosting the immune system
  • Helping to fight cancer cells
  • Reducing inflammation
  • Helping to treat HIV/AIDS and other diseases that can impact the immune system.

How Does Thymosin Alpha-1 Work?

Thymosin alpha-1 works by helping to regulate the immune system. It does this by binding to a protein called T cell receptor, which is found on the surface of T cells.

This interaction helps to activate the T cells, which then go on to attack and kill cancer cells or other cells that are causing disease.

3. CJC-1295

CJC-1295 is a synthetic peptide hormone that was developed to help with increasing muscle mass, reducing body fat, and improving overall physical performance.

It accomplishes this by increasing levels of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in the body.

CJC-1295 has been shown to be effective in increasing GH and IGF-1 levels in both young and old individuals.

Unfortunately, it is not currently approved for use in humans by the US Food and Drug Administration (FDA).

However, it is legal to purchase and use for research purposes.

Benefits of CJC-1295

The main benefit is its ability to increase GH and IGF-1 levels in the body.

This can lead to increased muscle mass, reduced fat mass, and improved overall physical performance.

CJC-1295 has also been shown to improve sleep quality and recovery from exercise.

When combined with Ipamorelin it works great for improving the health of skin cells.

How Does CJC-1295 Work?

CJC has been shown to increase growth hormone (GH) secretion from the anterior pituitary gland in vitro and in vivo.

It works by binding to the GHRH receptor on the pituitary gland. This causes an increase in the production of GH from the pituitary gland.

GH then travels through the blood to its target tissues, where it stimulates the growth of new cells and protein synthesis.

4. Ipamorelin

Ipamorelin is a growth hormone-releasing peptide and acts as a ghrelin hormone, similar to GHRP-2 and GHRP-6, but it is more selective in its action.

It was developed for the treatment of growth hormone deficiency and is effective in increasing growth hormone levels in youths and adults.

Ipamorelin is also being investigated for its potential use in the treatment of other conditions, such as obesity and type 2 diabetes.

Benefits of Ipamorelin

  • Stimulates the release of growth hormone
  • Effective in increasing bone density
  • Investigated for potential use in the treatment of other conditions
  • Improve the quality of life for those whose body stops producing enough growth hormone.
  • Help manage obesity and type 2 diabetes

It’s important to note that Ipamorelin is not FDA approved for human consumption.

How Does Ipamorelin Work?

Ipamorelin is administered as an injection under the skin.

It binds to the growth hormone-releasing hormone receptor (GHRHr) on the pituitary gland, which stimulates the release of growth hormone.

5. GHRP-2

GHRP-2 is a synthetic analog of human ghrelin, the natural hormone that stimulates appetite.

GHRP-2 is typically used as a research tool to study the effects of ghrelin on appetite, food intake, and body weight.

It is also sometimes used as a treatment for GH deficiency.

How Does GHRP-2 Work?

GHRP-2 works by mimicking the effects of ghrelin, the natural hormone that stimulates appetite.

Ghrelin is released by the stomach in response to fasting and signals the body to release growth hormone (GH).

GH, in turn, promotes cell growth and regeneration. GHRP-2 also increases levels of another hunger-stimulating hormone, called acylated ghrelin.

Benefits of GHRP-2

GHRP-2 has been shown to stimulate appetite and increase food intake in animals.

In one study, healthy adults given GHRP-2 ate about 30% more than those given a placebo.

GHRP-2 has also been shown to promote weight gain in people with GH deficiency.

Some other possible benefits include:

  • Improved sleep
  • Stronger immune system
  • Muscle growth

Who Should Not Take GHRP-2?

GHRP-2 should not be taken by people with ghrelinoma (a tumor of the ghrelin-producing cells in the stomach) or those who are sensitive to ghrelin.

It should also be used with caution in people with diabetes, as it can cause a potentially dangerous drop in blood sugar levels.

It is not approved for use in humans and should only be used for research purposes.

6. Vialox

Vialox (also called Pentapeptide-3V) originates from snake venom. This is a topical peptide that works similarly to botox.

What Are the Benefits of Vialox?

Pentapeptide-3V has been shown to have some benefits for the skin, including:

  • Reduces the appearance of fine lines and wrinkles
  • Eases headaches
  • Reduced muscle spasms

How Does Vialox Work?

Vialox attaches to AChR to reduce muscle contractions. This leads to relaxation and paralysis of the targeted area. In turn, reducing signs of aging skin.

It is typically applied to the skin as a cream or gel.

7. FOXO4-DRI

FOXO4-DRI is a drug that has been shown to extend lifespan in mice. It is a derivative of the hormone DHEA and works by activating the FOXO4 gene.

This gene is responsible for the production of antioxidants, which protect cells from damage.

FOXO4-DRI has been shown to increase lifespan, and it is thought that it could have similar effects in humans.

There are currently no clinical trials underway, but the drug is available for purchase online.

Some people are hesitant to take FOXO4-DRI, as it is a hormone derivative.

It is important to remember that the dose used in the studies was much lower than what is available for purchase.

Additionally, FOXO4-DRI has been shown to be safe and well-tolerated in mice.

Benefits of FOXO4-DRI

  • Improved weight management
  • Better blood sugar control
  • Reduced heart problems
  • Enhanced cognitive function

8. GHRP-6

GHRP-6 is sometimes referred to as “growth hormone releasing hexapeptide”, “GH-releasing peptide 6”, or “GHRP6”.

It is a synthetic analogue of the ghrelin hormone, the body’s natural “hunger hormone”.

Benefits of GHRP-6

GHRP-6 has been shown to:

  • Increase lean body mass
  • Reduce fat mass
  • Better overall body composition
  • Improve bone mineral density
  • Boosted stamina and energy levels
  • Faster recovery from exercise
  • Improve memory

How Does GHRP-6 Work?

GHRP-6 works to stimulate the release of growth hormone (GH) from the pituitary gland.

GH is responsible for many important physiological processes, including muscle growth, lipid metabolism, and bone mineralization.

It is commonly used in conjunction with a GHRH such as ModGRF1-29 or CJC-1295.

When used together, these compounds can provide a significant increase in growth hormone release.

9. BPC-157

BPC-157 is a peptide that has been shown to have a variety of healing properties. It has been shown to help with wound healing, gut health, and even brain function.

One of the most exciting things about BPC-157 is that it seems to help the body heal itself.

That means that it could potentially be used to treat a wide variety of conditions.

So far, there is a lot of promising research on BPC-157. However, more studies are needed to confirm its efficacy.

Benefits of BPC-157

The potential benefits of BPC-157 are vast. Here are just a few of the ways that this peptide could potentially be used:

  • Promoted wound and nervous system healing in a variety of animal studies.
  • Could potentially help with digestive issues.
  • It could potentially help with cognitive decline.
  • Used by the body to create new blood vessels
  • Shown to have anti-cancer properties in animal studies.
  • Shown to promote muscle growth in animal studies.
  • Could potentially be used to treat osteoporosis in humans.
  • Improved insulin sensitivity in animal studies.

The potential uses of BPC-157 are endless. This peptide has the potential to change the medical field as we know it.

How Does BPC-157 Work?

It works by stimulating the growth of new tissue and by preventing the formation of scar tissue.

10. GHK-Cu

GHK-CU is a peptide that has been shown to have anti-inflammatory and anti-aging properties. It is a small molecule that is derived from the human growth hormone.

It has been shown to increase collagen production, reduce wrinkles, and improve skin elasticity.

It has also been shown to stimulate hair growth and protect against hair loss.

GHK-CU is being studied as a potential treatment for inflammatory conditions such as arthritis, Crohn’s disease, and ulcerative colitis.

It is also being studied as a potential treatment for age-related diseases such as Alzheimer’s disease and Parkinson’s disease.

You can find it in cream, gel, and serum forms. Although it is not FDA approved.

How Does GHK-Cu Work?

It works by binding to copper ions, which then help to activate certain enzymes that are involved in the skin cell regeneration process.

11. Epitalon

Epitalon is a peptide that is known to increase the lifespan of cells. It has been shown to promote tissue regeneration and improve cognitive function.

Additionally, it has anti-aging properties and may be beneficial for preventing age-related diseases.

Benefits of Epitalon

The main benefits of Epitalon are its anti-aging properties, including:

  • Increased lifespan
  • Protection against age-related diseases
  • Improved cognitive function
  • May help to regenerate tissue and promote healing
  • Improvements in eyesight

How Does Epitalon Work?

Epitalon is a synthetic peptide that promotes the natural production of telomerase in human cells.

Telomerase is an enzyme that repairs and lengthens telomeres, the protective DNA sequences at the ends of chromosomes which naturally shorten as we age.

By promoting telomerase production, Epitalon helps keep cells young and healthy, slowing down the aging process.

12. Thymalin

Thymalin is a peptide hormone that is produced by the thymus. It plays a role in the immune system, specifically in the development of T cells.

Additionally, Thymalin is involved in the production of other hormones, such as adrenaline and cortisol.

It is important for the proper functioning of the immune system.

By helping to develop and maintain the activity of T cells, which are a type of white blood cell that is important for fighting infection.

It also helps to produce other hormones that are important for the body’s response to stress.

There is some scientific evidence to suggest that Thymalin may be helpful in the treatment of certain conditions, such as cancer and AIDS.

However, more research is needed to confirm these potential benefits.

13. Thymosin Beta-4

Thymosin beta-4 is a peptide that is known to promote cell growth and regeneration.

It has been shown to be effective in wound healing, tissue repair, and reducing musculoskeletal inflammation.

And has been investigated as a potential treatment for a range of diseases and conditions, including heart disease, stroke, infections, and chronic inflammatory conditions.

Thymosin beta-4 is naturally produced by the thymus gland and is involved in the development and function of the immune system.

It is also found in other tissues, including the brain, skin, and muscles.

While thymosin beta-4 has a range of potential uses, more research is needed to determine its safety and effectiveness.

14. Protirelin

Protirelin is a drug used to treat tumors of the thyroid gland. It is a synthetic version of the hormone thyrotropin-releasing hormone (TRH).

Protirelin is used to:

  • Treat Depression
  • Thyroid cancer
  • Regulate hormones

It is also being studied for use in other conditions.

How Does protirelin Work?

Protirelin works by stimulating the release of a thyroid-releasing hormone (TRH) from the pituitary gland.

TRH then stimulates the thyroid gland to secrete thyroid-stimulating hormone (TSH), which produces thyroxine (T4). This is involved in the regulation of metabolism.

Benefits of Protirelin

It has been shown to improve cognitive function, increase muscle mass, and reduce inflammation.

As we age, our cells become less efficient at repairing damage. Protirelin helps to counteract this by promoting healthy cell function.

15. MOTS-c

MOTS-c is a protein that is found in the mitochondria. It helps to regulate the production of energy in the cells.

When the cells don’t have enough energy, they can’t function properly. This can lead to various health problems.

MOTS-c is thought to be involved in the deterrence of obesity, type 2, and other metabolic disorders.

To date, there is no direct evidence that MOTS-c is involved in human health or disease.

However, the protein has been shown to be important in the reduction of obesity and type 2 diabetes in mice.

Potential Benefits of MOTS-c

  • Helps metabolism function
  • Better insulin sensitivity
  • May help with fat loss
  • May help prevent diseases like Osteoporosis
  • Anti-aging effects

How To Choose the Right Peptide for You

There are a lot of different peptides out there, so how do you know which one is right for you?

Here are a few things to consider:

1. What are your goals?

Do you want to lose weight? Boost your metabolism? Improve your skin and hair health?

Most peptides can help with these things, but some are better for certain goals than others.

Figure out what your main goal is and choose a peptide that will help you achieve it.

2. Do you have any health conditions?

Some peptides can interact with certain health conditions, so it’s important to be aware of any conditions you have before choosing a peptide.

If you have any concerns, speak to a doctor or healthcare professional before starting peptide therapy.

3. What is your budget?

Peptides can vary in price, so it’s important to find one that fits into your budget.

There are some cheaper options available, but they may not be as effective as the more expensive peptides.

4. Do you have any allergies?

Some peptides can cause allergic reactions in some people. If you have any allergies, make sure to check the ingredients list of the peptide before use.

5. Are you willing to inject?

In order to get the most out of peptides, they need to be injected. This can be done at home or by a professional.

If you’re not comfortable with needles, there are other peptides available, such as creams and gels.

These forms of anti-aging medicine typically contain hyaluronic acid to enhance skin tone.

Choosing the right peptide can seem overwhelming, but it doesn’t have to be.

Just take your time, do your research, and consult with your medical providers if you have any concerns.

Common Side Effects of Peptide Injections

Peptide injections are often celebrated for their anti-aging ability, but they can also cause a number of common side effects.

These side effects can include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach cramps
  • Headache
  • Dizziness
  • Fatigue
  • Infection

If you experience any of these side effects after receiving a peptide injection, be sure to contact your doctor or healthcare provider right away.

They can help you determine if the side effects are related to the injection or something else entirely.

Peptide injections are generally safe and well-tolerated, but it’s always important to be aware of the potential risks involved.

Tips for Administering Peptide Therapy Injections

Medical Syringe and Bottle for injection

Make sure you are well-informed about peptide therapy and the specific peptide you will be administering before starting injections.

  • Be familiar with the injection technique and how to properly administer the injection.
  • Always use a new syringe and needle for each injection to avoid any contamination.
  • Cleanse the injection site with an alcohol swab prior to injecting.
  • Inject the peptide into the fleshy part of your thigh or abdomen, avoiding any veins or arteries.
  • Lightly rewipe the injection site after injecting.
  • Drink plenty of water and stay hydrated after your injection.
  • Keep track of your injections, the amount of peptide injected, and any reactions or side effects you may experience.

Peptides for Anti Aging FAQs

What Is the Best Anti-Aging Peptide?

One of the best and most commonly used peptides is Sermorelin.

This anti-aging peptide helps to increase growth hormone production, which can help to improve skin elasticity, reduce sagging skin, and promote overall cell health.

Sermorelin also helps to boost immune function and improve sleep quality, both of which are important for maintaining a youthful appearance.

Can Peptides Reverse Aging?

Peptides are chains of amino acids that play an important role in the body, including in the aging process.

Some peptides have been shown to reverse aging signs or at least slow them down.

However, more research is needed to determine if peptides are an effective means of reversing aging.

What Peptides Make You Look Younger?

Some peptides that have been shown to have anti-aging effects include palmitoyl tetrapeptide-7, acetyl hexapeptide-8, and pentapeptide-3.

Which Is Better, Ipamorelin or Sermorelin?

Ipamorelin and sermorelin are both peptides that stimulate the pituitary gland to release growth hormone. They are often used to treat growth hormone deficiency.

However, there are some differences between the two peptides.

Ipamorelin is a more selective agonist of the growth hormone-releasing hormone (GHRH) receptor, which means it is more likely to stimulate the release of growth hormone than sermorelin.

Ipamorelin also has a longer half-life than sermorelin, meaning it stays in the body for longer.

Sermorelin, on the other hand, is a non-selective agonist of the GHRH receptor, which means it can stimulate the release of other hormones in addition to growth hormone.

Sermorelin also has a shorter half-life than ipamorelin.

So, what does this all mean?

Basically, ipamorelin is more likely to increase growth hormone levels than sermorelin.

However, sermorelin may be more effective at stimulating the release of other hormones, such as insulin-like growth factor 1 (IGF-1).

Ultimately, the choice of peptide depends on the goal of treatment.

If increasing growth hormone levels is the main goal, then ipamorelin may be the best option.

If stimulating the release of other hormones is the goal, then sermorelin may be a better choice.

Final Thoughts on Injection Peptide Therapies

Anti-aging Peptides are becoming more and more popular.

As people learn about their anti-aging benefits, they are looking for ways to include them in their own longevity routines.

In this article, I’ve outlined fifteen of the best peptides for anti-aging.

I’ve also provided a guide so that you can find the right peptide to achieve a more youthful appearance.

Let me know in the comments which one is your favorite!

Check out my review on Psychotic Pre-workout.

Sources:

https://www.peptidesciences.com/

https://evolvetelemed.com/peptides/cjc-1295-ipamorelin/

https://healthgains.com/faqs/is-sermorelin-fda-approved/

https://yuniquemedical.com/mots-c-peptide/

https://oaktonprimarycarecenters.com/services/musculoskeletal-peptides/

https://muscleandbrawn.com/peptides/how-to-inject-peptides/

https://biotechpeptides.com/2022/03/04/foxo4-dri-peptide-the-next-anti-aging-super-formula/

Eric Decremer
Eric Decremer

Eric is an ISSA Certified Personal Trainer and competes in the USPA Powerlifting Association. Feel free to contact him anytime at edecremer@wildnswole.com!

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